Sand Box

About Our Lab

The Tu Lab is interested in the study of metabolic cycles and how biological processes (e.g., cell growth and division, transcription, translation, mitochondrial homeostasis, autophagy) are coupled to metabolism and the metabolic state of a cell.


Featured Publications

Acetate dependence of tumors. Comerford SA, Huang Z, Du X, Wang Y, Cai L, Witkiewicz AK, Walters H, Tantawy MN, Fu A, Manning HC, Horton JD, Hammer RE, McKnight SL, Tu BP Cell 2014 Dec 159 7 1591-602

Npr2 inhibits TORC1 to prevent inappropriate utilization of glutamine for biosynthesis of nitrogen-containing metabolites. Laxman S, Sutter BM, Shi L, Tu BP Sci Signal 2014 7 356 ra120

Sulfur Amino Acids Regulate Translational Capacity and Metabolic Homeostasis through Modulation of tRNA Thiolation. Laxman S, Sutter BM, Wu X, Kumar S, Guo X, Trudgian DC, Mirzaei H, Tu BP Cell 2013 Jul 154 2 416-29